When you are hungry, you are not alone. When you are sick, you are not alone, either. The human body is home for tens of trillions of microbes, the most populated residence being the distal gut. Thanks to high-throughput metagenomic sequencing techniques, we do not have to coax each of them to grow on a plate or in a flask, in order to know who the bugs are and what genes they have. From just 1 gram of one's feces, there is plenty of genomic information for our gut microbial community, referred to as the gut microbiome.
Presented here is a high-quality reference gene catalog established from 1267 fecal samples and 1070 people around the world, including Danish, Spanish, Chinese and Americans. Details for how we did this, and how the Danish gut microbiome defers from the Chinese gut microbiome, could be found in our paper (Li, J. et al. An integrated catalog of reference genes in the human gut microbiome. Nat. Biotechnol. (2014).). You are welcomed to search for the microbial genes or download the data.
|#ORFs||% Complete ORFs||Total length (bp)||Average length (bp)||N50 (bp)||N90 (bp)||Max length||Min length||% annotated on Phylum level||% annotated on Genus level||% annotated on KO||% annotated on eggNOG|
*ORFs: open reading frame
*N50: it is the length for which the collection of all contigs of that length or longer contains at least half of the total of the lengths of the contigs
*N90: it is the length for which the collection of all contigs of that length or longer contains at least 90% of the total of the lengths of the contigs
*KO: KEGG orthologue group
*eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups)
See our paper for details.